Explore by Lab Marker
Nitrite
Urine Nitrite is a measure of the amount of nitrite in the urine. The presence of nitrite in the urine may indicate a urinary tract infection.
iollo markers that associate with Nitrite
Arginine
Arginine is the precursor for nitric oxide synthesis. Nitric oxide can be oxidized to form nitrite. Higher arginine availability may increase nitric oxide production and nitrite levels.References
References
Thiago Silveira Alvares, Carlos Adam Conte-Junior, Joab Trajano Silva, Vânia Margaret Flosi Paschoalin. Acute L-Arginine supplementation does not increase nitric oxide production in healthy subjects. Nutrition & Metabolism (2012). https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-9-54AK Kiani, G Bonetti, MC Medori, P Caruso, P Manganotti, F Fioretti, S Nodari, ST Connelly, M Bertelli. Dietary supplements for improving nitric-oxide synthesis. Journal Preventive Medicine and Hygiene (2022). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710401/
Asymmetric dimethylarginine
ADMA is an endogenous inhibitor of nitric oxide synthase. Higher ADMA levels can suppress nitric oxide production from arginine, potentially leading to reduced nitrite levels.References
References
Authors not specified in the provided snippet. Associations between asymmetric dimethylarginine (ADMA), nitrite-dependent renal carbonic anhydrase activity, and plasma testosterone levels. Journal of Inorganic Biochemistry (2017). https://www.sciencedirect.com/science/article/pii/S1109966617303949Larsen FS, et al.. Associations of Plasma Nitrite, l-Arginine and Asymmetric Dimethylarginine with Disease Severity and Outcome in Patients with Necrotizing Soft Tissue Infection. SHOCK (2018). https://journals.lww.com/shockjournal/fulltext/2018/06000/associations_of_plasma_nitrite,_l_arginine_and.8.aspx
Ornithine
Ornithine and citrulline can be interconverted in the urea cycle. Changes in ornithine levels may impact citrulline and downstream nitric oxide and nitrite production.References
References
Not specified. “Enzymes of Arginine Metabolism”. ScienceDirect (2023). https://www.sciencedirect.com/science/article/pii/S0022316623031206Not specified. “Urinary metabolites characteristic of urea-cycle amino acid deficiency”. The Journal of Clinical Investigation (1975). https://www.sciencedirect.com/science/article/abs/pii/0026049575901444Aleš Horák, Andrew E. Allen. “Common origin of ornithine–urea cycle in opisthokonts and stramenopiles”. Nature Communications (2020). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542463/