Indoor & Outdoor Allergies (varies regionally) are blood tests that measure levels of IgE antibodies to common indoor and outdoor allergens, which can help diagnose allergic rhinitis and other allergic conditions. The specific allergens tested may vary based on regional prevalence.

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iollo markers that associate with Indoor & Outdoor Allergies (varies regionally)*

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Docosahexaenoic acid

Docosahexaenoic acid (DHA), an omega-3 fatty acid, has anti-inflammatory properties and may help modulate the immune response in allergic conditions.
For the early and milder forms of allergic asthma, dietary supplementation with long-chain polyunsaturated fatty acids (LCPUFA), predominantly… Pollution and respiratory disease: can diet or supplements help? A review. Respiratory Research (2018). https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-018-0785-0Docosahexaenoic acid (Dha) … The External Exposome and Allergies: From the Perspective of the Epithelial Barrier Hypothesis. Journal of Allergy and Clinical Immunology (2022). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304993/

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Eicosapentaenoic acid

Eicosapentaenoic acid (EPA), another omega-3 fatty acid, also has anti-inflammatory effects and may influence allergic pathways.
Aktas, O., & Akdis, C.A.. Epithelial barrier hypothesis: Effect of the external exposome on allergic diseases. Frontiers in Immunology (2023). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306534/Del Duca, E., Sansone, A., Sgrulletti, M., Di Nolfo, F., Chini, L., Ferreri, C., & Moschese, V.. Fatty-Acid-Based Membrane Lipidome Profile of Peanut Allergy Patients: An Exploratory Study of a Lifelong Health Condition. International Journal of Molecular Sciences (2023). https://doi.org/10.3390/ijms24010120Koplin, J.J., et al.. Differential Effects of Obesity, Hyperlipidaemia, Dietary Intake and Physical Activity on Allergic Sensitization and Asthma in Children. Nutrients (2024). https://www.mdpi.com/2072-6643/14/11/2351Wu, D., et al.. Association Between Midpregnancy Polyunsaturated Fatty Acid Levels and Allergic Disease in Offspring. American Journal of Epidemiology (2023). https://academic.oup.com/aje/article/190/2/265/5900195

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Histamine

Histamine is a key mediator released by mast cells and basophils during allergic reactions. It contributes to symptoms like itching, swelling, and increased mucus production.
Kim, J. H., & Cho, S. H.. The Pathophysiology, Diagnosis and Treatment of Allergic Rhinitis - NCBI. Allergy, Asthma & Immunology Research (2009). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846743/Bousquet, J., et al.. Pollen respiratory allergy: Is it really seasonal? - PMC - NCBI. Clinical and Translational Allergy (2023). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384659/Bjermer, L., et al.. The complex pathophysiology of allergic rhinitis: scientific rationale … Allergy, Asthma & Clinical Immunology (2019). https://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0314-1Potapova, I. A., et al.. Respiratory sensitization to insect allergens: Species, components … Clinical and Experimental Allergy (2021). https://www.sciencedirect.com/science/article/pii/S1323893021000423