HIV 1 & 2 are the two main types of human immunodeficiency virus that can lead to AIDS. HIV infection can be diagnosed through blood tests that detect antibodies to the virus or viral RNA.

iollo markers that associate with HIV 1 & 2*


Kynurenine, a metabolite of tryptophan catabolism, is elevated in HIV infection due to increased immune activation and inflammation.


Phenylalanine metabolism may be altered in HIV infection. Phenylalanine is a precursor to dopamine which is dysregulated in HIV-associated neurocognitive disorders.


Tryptophan catabolism into kynurenine is increased by inflammation and immune activation in HIV infection, leading to lower tryptophan levels.