Lead is a toxic heavy metal that can accumulate in the body and cause neurological, reproductive, and other health problems. Measuring blood lead levels can help assess exposure and guide treatment, especially in children.

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iollo markers that associate with Lead

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5-Aminovaleric acid

5-Aminovaleric acid is a metabolite of lysine that can accumulate due to inhibition of lysine catabolism enzymes by lead toxicity. Elevated 5-aminovaleric acid may indicate impaired lysine metabolism from lead exposure.

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Homocysteine

Lead exposure is associated with elevated homocysteine levels, likely due to lead’s inhibition of enzymes in the methylation cycle that metabolize homocysteine. High homocysteine is a marker of impaired methylation and is associated with lead toxicity.