Alanine Aminotransferase (ALT)
Alanine Aminotransferase (ALT) is an enzyme found primarily in the liver. Elevated levels of ALT may indicate liver damage or disease.
iollo markers that associate with Alanine Aminotransferase (ALT)
Alanine
ALT catalyzes the transfer of an amino group from alanine to α-ketoglutarate, generating pyruvate and glutamate. Elevated alanine levels may reflect increased ALT activity and liver damage.
Aspartic Acid
Aspartate aminotransferase (AST), which is often elevated along with ALT in liver injury, catalyzes the transfer of an amino group from aspartate to α-ketoglutarate. Higher aspartate levels may occur with ALT elevations.
Glutamic Acid
ALT catalyzes the transfer of an amino group from alanine to α-ketoglutarate, generating glutamate. Increased glutamate levels may indicate higher ALT activity and liver injury.
Methionine
Abnormal methionine metabolism and elevated homocysteine are associated with liver damage and increased ALT levels. Impaired liver function affects methionine balance.
Phenylalanine
Liver damage impairs phenylalanine metabolism, potentially leading to higher levels. Phenylalanine elevations can occur with ALT elevations indicating hepatic dysfunction.
Tyrosine
Tyrosine metabolism occurs in the liver and can be disrupted by liver injury. Elevated tyrosine levels may be seen in parallel with increased ALT.