Alanine Aminotransferase (ALT) is an enzyme found primarily in the liver. Elevated levels of ALT may indicate liver damage or disease.

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iollo markers that associate with Alanine Aminotransferase (ALT)

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Alanine

ALT catalyzes the transfer of an amino group from alanine to α-ketoglutarate, generating pyruvate and glutamate. Elevated alanine levels may reflect increased ALT activity and liver damage.

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Aspartic Acid

Aspartate aminotransferase (AST), which is often elevated along with ALT in liver injury, catalyzes the transfer of an amino group from aspartate to α-ketoglutarate. Higher aspartate levels may occur with ALT elevations.

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Glutamic Acid

ALT catalyzes the transfer of an amino group from alanine to α-ketoglutarate, generating glutamate. Increased glutamate levels may indicate higher ALT activity and liver injury.

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Methionine

Abnormal methionine metabolism and elevated homocysteine are associated with liver damage and increased ALT levels. Impaired liver function affects methionine balance.

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Phenylalanine

Liver damage impairs phenylalanine metabolism, potentially leading to higher levels. Phenylalanine elevations can occur with ALT elevations indicating hepatic dysfunction.

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Tyrosine

Tyrosine metabolism occurs in the liver and can be disrupted by liver injury. Elevated tyrosine levels may be seen in parallel with increased ALT.