Explore by Lab Marker
Eosinophils
Eosinophils are a type of white blood cell involved in allergic reactions and parasitic infections. High levels of eosinophils can indicate these conditions.
iollo markers that associate with Eosinophils
Arachidonic acid
Arachidonic acid is converted to inflammatory leukotrienes that activate and attract eosinophils. Elevated arachidonic acid may indicate increased eosinophil-mediated inflammation.References
References
Drazen, J. M., Schaub, B., & Austen, K. F.. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and Associated Data. Proceedings of the National Academy of Sciences (2008). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206596/Blanchard, C., & Gleich, G. J.. Biology of the Eosinophil. Cold Spring Harbor Perspectives in Biology (2010). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109275/Majumdar, S. K., & Chatterjee, A.. Emerging Roles of Eosinophils and Eosinophil-Derived Lipid Mediators in Health and Disease. Frontiers in Immunology (2012). https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2012.00270/full
Histamine
Histamine released by mast cells and basophils can activate eosinophils and increase their levels. Elevated histamine may suggest an allergic response involving eosinophils.References
References
Hartwig C, Munder A, Glage S, Wedekind D, Schenk H, Seifert R, et al.. “In vivo Evidence for Partial Activation of Eosinophils via the Histamine H4 Receptor”. Frontiers in Immunology (2018). https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.02119/fullnan. “Eosinophil - an overview”. ScienceDirect Topics (nan). https://www.sciencedirect.com/topics/medicine-and-dentistry/eosinophil