Eosinophils are a type of white blood cell involved in allergic reactions and parasitic infections. High levels of eosinophils can indicate these conditions.
Arachidonic acid is converted to inflammatory leukotrienes that activate and attract eosinophils. Elevated arachidonic acid may indicate increased eosinophil-mediated inflammation.
Drazen, J. M., Schaub, B., & Austen, K. F.. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and Associated Data. Proceedings of the National Academy of Sciences (2008). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206596/
Histamine released by mast cells and basophils can activate eosinophils and increase their levels. Elevated histamine may suggest an allergic response involving eosinophils.