Neutrophils
Neutrophils are a type of white blood cell that help fight bacterial infections. Low levels of neutrophils can increase the risk of infection.
iollo markers that associate with Neutrophils
Arachidonic acid
Arachidonic acid is released from neutrophil membranes and metabolized to pro-inflammatory eicosanoids that amplify the inflammatory response and neutrophil activation.
References
References
Hatem Tallima, Rashika El Ridi. Arachidonic acid: Physiological roles and potential health benefits - NCBI. NCBI (2019). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052655/
M.A. Khan, S.M. Fischer. Arachidonic acid aggregates neutrophils - SpringerLink. SpringerLink (1989). https://link.springer.com/article/10.1007/BF00913500
M.A. Khan, S.M. Fischer. A possible role of arachidonic acid in human neutrophil aggregation and chemotaxis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (1990). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042398/
Docosahexaenoic acid
Docosahexaenoic acid is an omega-3 fatty acid that gets incorporated into neutrophil membranes and can modulate neutrophil function by reducing pro-inflammatory mediator production.
References
References
Calder, P. C.. Effects of Omega-3 Fatty Acids on Immune Cells. Frontiers in Immunology (2017). https://doi.org/10.3389/fimmu.2017.00557