Carbon Dioxide (CO2) is an electrolyte that helps regulate the body’s acid-base balance. Abnormal levels of CO2 may indicate respiratory or metabolic problems.
Alanine is metabolized to pyruvate which can be converted to lactate, contributing to lactic acidosis and increased CO2 levels during anaerobic metabolism.
R. J. W. Arts, J. C. M. Bakker, J. W. Koster, and J. F. M. Westerhof. Comprehensive review on lactate metabolism in human health literature. Mitochondrion (2014). https://pubmed.ncbi.nlm.nih.gov/24929216/
Succinic acid is an intermediate in the citric acid cycle. Disruption of aerobic cellular respiration can lead to buildup of succinic acid, contributing to metabolic acidosis and increased CO2.
Dägele D, Scholten E, Renz T, Thomas J, Sinkler R, Both-Fodor M, Antal E, Sz L, Miklóssy I. Substrate type and CO2 addition significantly influence succinic acid production. Biotechnology Letters (2023). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432361/
