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Mean Corpuscular Hemoglobin Concentration (MCHC) is a measure of the average concentration of hemoglobin in each red blood cell. Abnormal MCHC may indicate certain types of anemia or other blood disorders.

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iollo markers that associate with Mean Corpuscular Hemoglobin Concentration (MCHC)

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Glycine

Glycine is involved in heme biosynthesis, which is a key component of hemoglobin. Changes in glycine levels may impact hemoglobin production and MCHC.
Li, X., Sun, L., Zhang, W., et al.. Association of serum glycine levels with metabolic syndrome in an elderly Chinese population. Nutrition & Metabolism (2018). https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-018-0325-4Mitchell, J., et al.. A method for measuring meaningful physiological variables in fish blood. Scientific Reports (2023). https://www.nature.com/articles/s41598-023-28061-w

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Succinic acid

Succinic acid is an intermediate in the citric acid cycle, which generates energy for heme synthesis. Alterations in succinic acid may affect hemoglobin production and MCHC.
The Carter Center. Hematology - The Carter Center. nan (nan). https://www.cartercenter.org/resources/pdfs/health/ephti/library/lecture_notes/med_lab_tech_students/ln_hematology_mlt_final.pdfnan. The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult … JAMA Network Open (2020). https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2772395nan. Association of serum selenium with anemia‐related indicators and risk … Wiley Online Library (2021). https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.2261nan. Adenylosuccinic Acid Is a Non-Toxic Small Molecule In Vitro and In Vivo. NCBI (2023). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609790/nan. Succinate dehydrogenase inversely regulates red cell distribution width … NCBI (nan). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536274/
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