Mean Corpuscular Hemoglobin Concentration (MCHC)
Mean Corpuscular Hemoglobin Concentration (MCHC) is a measure of the average concentration of hemoglobin in each red blood cell. Abnormal MCHC may indicate certain types of anemia or other blood disorders.
iollo markers that associate with Mean Corpuscular Hemoglobin Concentration (MCHC)
Glycine
Glycine is involved in heme biosynthesis, which is a key component of hemoglobin. Changes in glycine levels may impact hemoglobin production and MCHC.
References
References
Li, X., Sun, L., Zhang, W., et al.. Association of serum glycine levels with metabolic syndrome in an elderly Chinese population. Nutrition & Metabolism (2018). https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-018-0325-4
Mitchell, J., et al.. A method for measuring meaningful physiological variables in fish blood. Scientific Reports (2023). https://www.nature.com/articles/s41598-023-28061-w
Succinic acid
Succinic acid is an intermediate in the citric acid cycle, which generates energy for heme synthesis. Alterations in succinic acid may affect hemoglobin production and MCHC.
References
References
The Carter Center. Hematology - The Carter Center. nan (nan). https://www.cartercenter.org/resources/pdfs/health/ephti/library/lecture_notes/med_lab_tech_students/ln_hematology_mlt_final.pdf
nan. The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult … JAMA Network Open (2020). https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2772395
nan. Association of serum selenium with anemia‐related indicators and risk … Wiley Online Library (2021). https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.2261
nan. Adenylosuccinic Acid Is a Non-Toxic Small Molecule In Vitro and In Vivo. NCBI (2023). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609790/
nan. Succinate dehydrogenase inversely regulates red cell distribution width … NCBI (nan). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536274/