> ## Documentation Index
> Fetch the complete documentation index at: https://markers.iollo.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Neutrophils

Neutrophils are a type of white blood cell that help fight bacterial infections. Low levels of neutrophils can increase the risk of infection.

## iollo markers that associate with Neutrophils

### Arachidonic acid

Arachidonic acid is released from neutrophil membranes and metabolized to pro-inflammatory eicosanoids that amplify the inflammatory response and neutrophil activation.

<Accordion title="References">
  Hatem Tallima, Rashika El Ridi. Arachidonic acid: Physiological roles and potential health benefits - NCBI. *NCBI* (2019). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052655/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052655/)

  M.A. Khan, S.M. Fischer. Arachidonic acid aggregates neutrophils - SpringerLink. *SpringerLink* (1989). [https://link.springer.com/article/10.1007/BF00913500](https://link.springer.com/article/10.1007/BF00913500)

  M.A. Khan, S.M. Fischer. A possible role of arachidonic acid in human neutrophil aggregation and chemotaxis. *Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids* (1990). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042398/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042398/)
</Accordion>

### Docosahexaenoic acid

Docosahexaenoic acid is an omega-3 fatty acid that gets incorporated into neutrophil membranes and can modulate neutrophil function by reducing pro-inflammatory mediator production.

<Accordion title="References">
  Calder, P. C.. Effects of Omega-3 Fatty Acids on Immune Cells. *Frontiers in Immunology* (2017). [https://doi.org/10.3389/fimmu.2017.00557](https://doi.org/10.3389/fimmu.2017.00557)
</Accordion>