> ## Documentation Index
> Fetch the complete documentation index at: https://markers.iollo.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Hematocrit

Hematocrit is a measure of the percentage of red blood cells in the blood. Low hematocrit levels (anemia) can cause fatigue, shortness of breath, and other symptoms.

## iollo markers that associate with Hematocrit

### Alanine

Alanine is involved in the synthesis of heme, a key component of hemoglobin in red blood cells. Changes in alanine levels may therefore correlate with hematocrit, a measure of red blood cell volume.

<Accordion title="References">
  Liu, Y., et al.. Serum alanine aminotransferase is correlated with ... - PubMed literature. *PubMed* (2012). [https://pubmed.ncbi.nlm.nih.gov/22486855/](https://pubmed.ncbi.nlm.nih.gov/22486855/)

  Shen, X., et al.. Serum Alanine Aminotransferase Levels, Hematocrit Rate and Body .... *ScienceDirect* (2022). [https://www.sciencedirect.com/science/article/pii/S1807593222025340](https://www.sciencedirect.com/science/article/pii/S1807593222025340)

  Liu, Y., et al.. Serum alanine aminotransferase is correlated with hematocrit in ... - NCBI. *NCBI* (2014). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213065/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213065/)

  Liu, Y., et al.. Serum alanine aminotransferase is correlated with hematocrit in .... *Taylor & Francis Online* (2011). [https://www.tandfonline.com/doi/pdf/10.3109/00365513.2012.660536](https://www.tandfonline.com/doi/pdf/10.3109/00365513.2012.660536)
</Accordion>

### Glycine

Glycine is another amino acid involved in heme biosynthesis. Alterations in glycine availability could potentially impact hemoglobin production and thus hematocrit levels.

<Accordion title="References">
  Stachlewitz RF, et al.. "Glycine reduces platelet aggregation - PMC - NCBI". *Cardiovasc Res.* (1995). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167623/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167623/)

  Bunn HF, et al.. "Extracellular glycine is necessary for optimal hemoglobinization ... - NCBI". *Blood* (2017). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541866/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541866/)
</Accordion>