> ## Documentation Index
> Fetch the complete documentation index at: https://markers.iollo.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Food Allergy Profile (IgE)*

Food Allergy Profile (IgE) is a blood test that measures levels of IgE antibodies to specific foods, which can help diagnose food allergies.

## iollo markers that associate with Food Allergy Profile (IgE)\*

### Arachidonic acid

Arachidonic acid is an omega-6 fatty acid that can be converted to pro-inflammatory eicosanoids. Elevated arachidonic acid levels may promote allergic inflammation and increase IgE levels in some individuals.

<Accordion title="References">
  L. M. Ferreira, M. C. R. Nunes, S. A. P. Silva, C. M. S. Soares, J. M. S. Silva, I. M. S. C. Moreira, and J. A. S. Coutinho. Fatty-Acid-Based Membrane Lipidome Profile of Peanut Allergy Patients. *Nutrients* (2022). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820545/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820545/)

  Y. Zhang, Y. Zhou, Y. Zhu, Y. Zhang, and X. Chen. Combined Supplementation with Arachidonic and Docosahexaenoic Acids Ameliorates Allergen-Induced Dermatitis in Mice. *Journal of Agricultural and Food Chemistry* (2022). [https://www.sciencedirect.com/science/article/pii/S0022316622007192](https://www.sciencedirect.com/science/article/pii/S0022316622007192)

  Hatem Tallima and Rashika El Ridi. Arachidonic Acid: Physiological Roles and Potential Health Benefits. *Nutrients* (2019). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052655/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052655/)
</Accordion>

### Docosahexaenoic acid

Docosahexaenoic acid (DHA) is an omega-3 fatty acid with anti-inflammatory properties. Higher DHA levels may help reduce allergic inflammation and IgE production in some people.

<Accordion title="References">
  Zhang, J., Zhao, Y., & Huang, J.. DHA-Rich Tuna Oil Effectively Suppresses Allergic Symptoms in Mice. *Science Direct* (2022). [https://www.sciencedirect.com/science/article/pii/S0022316622010665](https://www.sciencedirect.com/science/article/pii/S0022316622010665)

  Calder, P. C.. Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases. *Journal of Allergy and Clinical Immunology* (2015). [https://www.sciencedirect.com/science/article/pii/S1323893014000100](https://www.sciencedirect.com/science/article/pii/S1323893014000100)

  Zhang, Y., & Spite, M.. The Influence of Dietary Fatty Acids on Immune Responses. *MDPI* (2017). [https://www.mdpi.com/2072-6643/11/12/2990](https://www.mdpi.com/2072-6643/11/12/2990)

  Ahmed, N., Barrow, C. J., & Suphioglu, C.. Exploring the Effects of Omega-3 and Omega-6 Fatty Acids on Allergy Using a HEK-Blue Cell Line. *Nutrients* (2016). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783952/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783952/)
</Accordion>

### Eicosapentaenoic acid

Like DHA, eicosapentaenoic acid (EPA) is an anti-inflammatory omega-3 fatty acid. Adequate EPA levels may have a protective effect against allergies and elevated IgE.

<Accordion title="References">
  C. E. Fiocchi, K. E. Cox, M. C. Coulthard, R. J. Boyle, L. A. Hosking, C. Taggart, J. P. Warner, S. Garcia-Larsen, A. Venter, S. A. Robertson, S. T. Holt, and R. L. Prescott. The Effect of Maternal Omega-3 Fatty Acid Supplementation on Infant Allergy. *Current Allergy and Asthma Reports* (2014). [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961846/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961846/)
</Accordion>