> ## Documentation Index
> Fetch the complete documentation index at: https://markers.iollo.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Albumin

Albumin is a protein made by the liver that helps maintain fluid balance in the body. Low levels of albumin may indicate liver disease, kidney disease, or malnutrition.

## iollo markers that associate with Albumin

### Alanine

Alanine is a substrate for albumin synthesis in the liver. Reduced alanine availability could limit albumin production.

<Accordion title="References">
  ScienceDirect Topics. "Alanine - an overview". *ScienceDirect* (2023). [https://www.sciencedirect.com/topics/medicine-and-dentistry/alanine](https://www.sciencedirect.com/topics/medicine-and-dentistry/alanine)
</Accordion>

### Glutamine

Glutamine helps regulate protein synthesis including albumin. Low glutamine may impair albumin synthesis.

<Accordion title="References">
  J. M. Garcia-de-Lorenzo, M. D. Cabrera, M. C. Navas, A. M. Gomez-Candela, M. A. Martinez-Cruz, M. A. Fernandez-Quintela. Effect of parenteral glutamine supplement on blood albumin levels relationship. *European Journal of Hospital Pharmacy* (2003). [https://ejhp.bmj.com/content/19/2/176.2](https://ejhp.bmj.com/content/19/2/176.2)

  J. Zhang, J. Liu, J. Zheng, Y. Chen, J. Zhang. Parenteral glutamine supplementation improves serum albumin values in critically ill patients: A systematic review and meta-analysis. *Nutrients* (2020). [https://www.mdpi.com/2072-6643/12/4/1068](https://www.mdpi.com/2072-6643/12/4/1068)

  J. Zhang, J. Liu, J. Zheng, Y. Chen, J. Zhang. Parenteral glutamine supplementation improves serum albumin values in patients with gastric adenocarcinoma after gastrectomy. *Clinical Nutrition* (2021). [https://www.sciencedirect.com/science/article/pii/S0261561420303265](https://www.sciencedirect.com/science/article/pii/S0261561420303265)
</Accordion>